In March 2021, Drs. Gerszten and Sarzynski (MPIs) received a 5-yr R01 grant from the National Institute of Nursing Research for a project utilizing data and specimens from HERITAGE, among other studies. The project seeks to identify comprehensive plasma molecular signatures (metabolites & proteins) of exercise responsiveness for VO2max, insulin sensitivity, visceral fat, and HDL-cholesterol, as well as examine whether biomarkers of exercise response are potentially causally related to relevant cardiometabolic traits and outcomes. A summary of the grant can be found below:
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